Corning Cell Counter
Counting cells is a routine task for any researcher working with cell cultures. Obtaining accurate cell counts is important for both cell expansion as well as cell seeding for experiments. Automated cell counting can speed-up your workflow and eliminate user-to-user differences.
The name Corning Cell Counter comes from our agreement with Corning on the distribution of our product. We have come to an agreement for the exclusive distribution of our cell counting technology, hence the name Corning Cell Counter.
Small footprint, reduces waste and looks good too!
"High quality results and easy to use. I particularly like the fact that reusable glass hemocytometers are used, reducing waste and running costs."
Great device, saves a lot of time
"Easy to use, high quality and reproducible cell counting. Customer support is very professional."
"Everyone in the lab is pretty enthusiastic about the cell counter compared to the alternative or formerly applied methods/devices for a number of reasons: tiny dimensions of the device, easily installed, intuitive use (check the YouTube video!), improved data quality, less time consuming working step. For a quick estimation of the cell number: suspension cells can even be directly measured in the culture flask without loading onto the counting chamber."
Great staple for cell culture!
"The Corning Cell Counter has become a staple in my cell culture lab. It's easy and fast assessment of cell density is something that I rely on every day. It is a product that gives reliable results, and I love that I can see both the raw images and the analyzed images easily."
A time saver
"Absolutely. Very easy to use, and yields reproducible results. We are able to quickly perform cell counts on dozens of samples in rapid succession - whereas the traditional methods for trypan blue counting were much more labor intensive."
Counting is fast and reliable. I would definitely buy it again.
"We compared the cell counter with manually counting. The data matches very nicely if you do not overload the slides with too high a cell density. To get reliable data, high debris content should also not be present."
Real time gating
Adapt size gating to your cells
The Corning Cell Counter generates images that are automatically analyzed using our state-of-the-art cell counting algorithm. Images are analyzed within seconds and can be used to count both mammalian cells and organoids. This allows you to quickly obtain an accurate overview of the cell concentration of your sample. Users can optimize their cell counts by gating the size range to the cell type that is being used. The gates and corresponding concentration, cell size and viability analysis can be adapted in real time.
Obtain cell population number and size
All your sample data in one place.
Images and numerical data of the cell counts are collected into an online report. The report provides an overview of the cell concentration, size and, if desired, cell viability. Reports and raw images can be stored online in the CytoSMART Cloud environment and are always available for download.
Identify single cells in clusters
The analysis is effective in single cell recognition, even for sticky cells
To identify single cells using image analysis is relatively straightforward. Cell recognition can be achieved using small parameter sets that contain features like cell size, edge thickness and circularity. Some cell types however are known to stick together and as a consequence would be difficult to single out. The image analysis algorithms in the Corning Cell Counter are supported by machine learning where the parameter set has been extended to three-hundred and fifty thousand and is optimized to clearly distinguish cell boundaries, even in samples that are highly crowded.
Want to see if the Corning Cell Counter is a good fit for your Lab?
Organoid Counting - New Feature
Perform organoid counts on your own transparent counting slide
The popularity of organoid culturing has spiked in the past decade since the publication of Sato et al. 2009, in which the development of intestinal crypt-villus structures is postulated. The three-dimensional niche-like structures within organoids are highly similar to in situ physiology. While these structures have a high potential in many life-science research fields, they are laborious to develop and maintain. The Corning Cell Counter can be equipped with an algorithm for organoid counting that can be used to standardize and speed-up a routine part of organoid culturing.
Determine sample variance
Improve your data accuracy by increasing the counting area
The multi-count function of the Corning Cell Counter allows users to take up to 8 counts of the same sample. When multiple counts are taken at various locations within the hemocytometer, the variability between counts can be investigated. The software allows for easy numerical and visual comparison between selected counts, including the calculation of averages and standard deviation.
Use the counting chamber that you already own
Compatible with hemocytometers and other transparent counting chambers
The Corning Cell Counter is developed to be used in combination with hemocytometers or any other transparent (disposable) counting slide, with or without a counting grid. Use reusable glass hemocytometers when you would like to reduce both operational costs and the environmental footprint of your lab. The only requirement of the counting slide is the depth, which needs to be 0.1 mm for mammalian cells and can be 0.2 mm for organoids.
|Counting range (concentration/mL)||(5.0 × 10^4) – (1.0 × 10^7)|
|Size range - mammalian cells||4 – 70 µm|
|Size range - organoids||10 – 100 µm/200 µm|
|Measurement time**||<3 sec|
|Field of view||1.5 mm × 1.5 mm|
|Magnification||10× (0.96 µm/pixels)|
|Image resolution||1536 × 1536 pixels|
|Data formats||JPG, CSV, PDF|
|Camera||5.0 MP CMOS|
|Dimensions (L × W × H)||122 mm × 122 mm × 125 mm|
|Operating environment||5 – 40 °C, 20 – 95% humidity|
|Research use only. Not intended for diagnostic purposes|
|* size limit depends on the dimensions of the counting chamber|
|** at 73 Mbps download and 20 Mbps upload speed|
Frequently Asked Questions
When using Trypan Blue, the device can determine cell viability as well.
The device is easy to clean using lint-free wipes and ethanol (70%) or isopropyl alcohol (IPA). Do not use acetone to clean the device, also the device cannot be autoclaved.
The Corning Cell Counter is compatible with reusable (glass) and disposable (plastic) counting chambers.
No calibration of the device is required.
The device requires a dedicated desktop or laptop running on Windows 10 or above, with a USB3 port and an active internet connection. A WiFi or Ethernet connection is necessary for connecting to the CytoSMART Cloud for image analysis and storage.